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Central Line-Associated Bloodstream Infection (CLABSI) Standardized Infection Ratio

CMS Measures Inventory Tool (CMIT) ID
00460-01-C-PCHQR
Steward Organization Group
Centers for Disease Control and Prevention
Committee
MSR Recommendation Group
    Measure Overview
      Use in CMS Programs
      CMS Program History
      • Finalized for inclusion in the PPS-Exempt Cancer Hospital Quality Reporting (PCHQR) Program in 2011. 
      • Implemented in the PCHQR Program in 2013.
      • Also active in the Long-Term Care Hospital Quality Reporting Program.
      Description

      Annual risk-adjusted standardized infection ratio (SIR) of central line-associated bloodstream infections (CLABSI) among adults and children hospitalized as inpatients at acute care hospitals, critical access hospitals, oncology hospitals, and long-term acute care hospitals. SIR is reported annually and is calculated by dividing the number of observed CLABSIs by the number of predicted CLABSIs.  

      Numerator

      Number of annually observed central line-associated bloodstream infections (CLABSI) in hospital inpatients. 

      Numerator Exclusions

      N/A

      Numerator Exceptions

      N/A

      Denominator

      Number of annually predicted central-line associated bloodstream infections (CLABSI) in hospital inpatients.

      Denominator Exclusions

      The following devices are not considered central lines and are excluded:  

      • Arterial catheters unless in the pulmonary artery, aorta or umbilical artery 
      • Arteriovenous fistula  
      • Arteriovenous graft  
      • Extracorporeal life support (ECMO)  
      • Hemodialysis reliable outflow (HERO) dialysis catheter  
      • Intra-aortic balloon pump (IABP) devices  
      • Peripheral IV or Midlines  
      • Ventricular Assist Device (VAD) 

      CLABSI events reported to NHSN as mucosal barrier injury laboratory-confirmed bloodstream infections (MBI-LCBIs) are excluded. 

      Denominator Exceptions

      N/A

      Cascade of Meaningful Measures Priority
      Measure Type
      Outcome
      Level of Analysis
      Facility
      Care Setting
      Hospital: Inpatient Acute Care Facility
      Hospital: Long-Term Care
      PPS-Exempt Cancer Hospital
      Types of Data Sources
      Electronic Health Records
      Paper Patient Medical Records
      CBE Endorsement Status
      Endorsed
      CBE Endorsement History

      Endorsement History: 

      • Initial endorsement, 2012. 
      • Measure retained endorsement in 2025 through maintenance cycle as new measure ID CBE #0139.

       Link to Endorsement Measure Record: Catheter-Associated Urinary Tract Infection (CAUTI) Standardized Infection Ratio | Partnership for Quality Measurement

        About this Analysis (Measure Score by PY)

        Impact Summary: By evaluating outcomes such as health care-associated infections across different inpatient care settings and reporting on these results at the facility, hospital, or agency level, this measure helps fulfill Prospective Payment System-Exempt Cancer Hospital Quality Reporting (PCHQR) Program goals by providing actionable quality-of-care information that empowers consumers and drives hospitals and clinicians to improve infection-prevention practices for Medicare beneficiaries. 

        Overall, the limited number of PPS-exempt cancer hospitals participating and reporting in this program makes it difficult to analyze overall performance trends. As shown in Table 1, if all entities performed at 2024’s average score, about 60 fewer negative outcomes could occur. This translates to about five patients per entity and means that improving performance on this measure could help ensure that fewer patients contract CLABSI, potentially leading to better health outcomes.

        For this measure, Battelle reviewed the following publicly available datasets available at  Hospitals data archive | Provider Data Catalog:

        • Hospitals_02_2026.zip (which contains data from April 2024-March 2025 and is referred to as year 2024 in this assessment)
        • Hospitals_02_2025.zip (which contains data from April 2023-March 2024 and is referred to as year 2023 in this assessment)
        • Hospitals_01_2024.zip (which contains data from April 2022-March 2023 and is referred to as year 2022 in this assessment)
        • Hospitals_01_2023.zip (which contains data from April 2021-March 2022 and is referred to as year 2021 in this assessment)

        Battelle analyzed all values for “PCH_4” not marked as “Not Available” from the corresponding PCH_HEALTHCARE_ASSOCIATED_INFECTIONS_HOSPITAL.csv file.

         

        About Figure 1: Figure 1 is a boxplot that shows how scores have changed based on the most recent 4 years of data available. For each year, the boxplot displays a box with lines and dots to help visualize the range and distribution of scores. The dots represent the points where the lowest 5% and highest 5% of scores fall, and the line connecting them shows where 90% of the scores are located. The box itself covers the middle half of the scores, from the 25th to the 75th percentile. Inside the box, a horizontal line marks the median score, which is the middle value, while a “+” sign shows the average score. This type of graph makes overall trends in scores over time as well as the consistency and spread of the results easier to understand.

        Figure 1 (Measure Score by PY)
        boxplot

        Figure 1. Boxplot of Measure Score by Year

        Interpretation (Measure Score by PY)

        Figure 1 Interpretation: There are only 11 entities per year, so any apparent trend may just as likely be attributed to random error, indicating little discernible change across the 4 years. Overall, the limited number of PPS-exempt cancer hospitals participating and reporting in this program makes it difficult to analyze overall performance trends. For this measure, a lower score indicates better quality of care.

        About this Analysis (Score Distro)

        About Table 1: Table 1 illustrates the distribution of scores (standardized infection ratio [SIR]), raw rates, and the number of patients represented within each group. It is important to note that the groups (referred to as deciles, each comprising 10% of the organizations) with the lowest or highest scores may contain more or fewer patients than other groups. For example, if the lowest-scoring decile includes only 5% of the total patient population, then smaller entity size may be associated with lower performance scores.

        Table 1 (Score Distro)

        Table 1. Importance in the Most Recent Year of Data Available (Decile by Measure Score, 2024) 

         OverallDecile 1Decile 2Decile 3Decile 4Decile 5Decile 6Decile 7Decile 8Decile 9Decile 10
        Average SIR (Standard Deviation)

        1.174 (0.601)

        0.245

        0.977

        0.896

        0.937

        1.292

        1.375

        1.559

        1.330

        2.089

        1.973

        Average Raw Rate (Standard Deviation)

        0.127 (0.070)

        0.025

        0.089

        0.112

        0.116

        0.126

        0.138

        0.142

        0.149

        0.231

        0.247

        Entities

        11

        2

        1

        1

        1

        1

        1

        1

        1

        1

        1

        Patients

        476,883

        156,339

        12,403

        56,402

        91,284

        58,517

        33,215

        7,032

        49,567

        6,058

        6,066

        Interpretation (Score Distro)

        Table 1 Interpretation: To estimate the number of negative outcomes (CLABSI), the number of patients is multiplied by the average raw rate for each decile. In 2024, the total estimated number of negative outcomes across all deciles is about 450. If the average performance of Decile 3 (0.112%) is considered a plausible, achievable rate, and the entities in Deciles 4 through 10 improved to reach that rate, about 60 fewer negative outcomes could occur. This translates to about five patients per entity and means that improving performance on this measure could help ensure that fewer patients contract CLABSI, potentially leading to better health outcomes.

          Importance Criterion Definition

          The Meaningfulness criterion will be evaluated as part of the full Preliminary Assessment available in September. 

            Criterion Definition

            This criterion will be evaluated as part of the full Preliminary Assessment available in September. 

              Criterion Definition

              This criterion will be evaluated as part of the full Preliminary Assessment available in September. 

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